Summary: Purisaki contains 13 plant-based ingredients — berberine, fucoxanthin, pomegranate oil, green tea extract, African mango extract, vitamins B1/B3/C, and 5 additional botanical extracts — all delivered transdermally over 8 hours for steady, consistent absorption.
Berberine Extract
The cornerstone ingredient. Berberine is an alkaloid from barberry, goldenseal, and Oregon grape with one of the most extensive natural compound research bases. Key mechanisms documented at PubMed: AMPK activation, GLUT4 upregulation for cellular glucose uptake, reduced hepatic gluconeogenesis, improved insulin receptor sensitivity, and lipid-lowering via LDL receptor upregulation.
Fucoxanthin Extract
A marine carotenoid from brown seaweed that activates UCP1 (uncoupling protein 1) in white adipose tissue — a thermogenic mechanism complementary and additive to berberine's AMPK pathway. The combination targets metabolic balance through two independent biological routes. Research is indexed at the NCBI.
Pomegranate Oil (Punicic Acid)
Cold-pressed from pomegranate seeds. Rich in punicic acid — a conjugated linolenic acid with documented antioxidant and body composition support properties. As a topical ingredient, it also provides direct skin nourishment and radiance support at application sites.
Green Tea Extract (EGCG)
Standardized for epigallocatechin gallate — the most active catechin in green tea. EGCG activates thermogenic pathways, provides potent antioxidant protection, and supports sustained mental alertness. Research across dozens of clinical trials confirms metabolic support effects.
African Mango Extract (Irvingia gabonensis)
Seed extract that supports adiponectin and leptin sensitivity — hormones governing insulin response and appetite regulation. Clinical publications document meaningful effects on body composition and satiety with consistent use.
Vitamins B1 (Thiamine), B3 (Niacin), and C
Metabolic cofactors: Thiamine powers carbohydrate-to-ATP conversion. Niacin supports NAD+ production critical for cellular energy metabolism. Vitamin C provides antioxidant support and cofactor function across multiple metabolic enzyme systems.
5 Additional Botanical Extracts
The complete formula includes five more botanical extracts selected to complement and amplify the core ingredients — providing comprehensive metabolic, antioxidant, and vitality support in a single daily patch application.